Anti-Inflammatory and Anticancer Activities of Hedyotis capitellata Growing in Vietnam
نویسندگان
چکیده
Hedyotis capitellata has widely used in traditional medicine for treatment of toxication, inflammation, diuretic, stomachache. H. capitellata has been showed to have antioxidant, anti-inflammatory and antibacterial effects. In this study we presented the acute and chronic anti-inflammatory and anticancer activities on HeLa, MCF7 and N87 cells line of H. capitellata. Our data showed that H. capitellata aqueous total extract has acute and chronic anti-inflammation activity in dose-dependent manner. Ethyl acetate fraction and Water fraction of H. capitellata showed strong cytotoxicity on MCF7 cells line with IC of 64.50 μg/ml and 34.38 μg/ml, 50 respectively; but did not have effect on cervical cancer cell line (HeLa) and stomach cancer cell line (N87).
منابع مشابه
New Anthraquinone and Iridoid Glycosides from the Stems of Hedyotis hedyotidea
Introduction. – The genus Hedyotis (Rubiaceae family) contains 69 species distributed in China [1], some of which have been used as Traditional Chinese Medicines (TCM), such as Hedyotis diffusa for treating cancer, and Hedyotis chrysotricha for treating enteritis [2]. The characteristic chemical constituents of this genus are anthraquinones, flavonoids, iridoids, and triterpenoids [3]. Plants o...
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